Healthcare Professionals

Build the foundation for your depression care from the start

DEPLIN® targeted medical nutrition helps restore brain chemistry by supporting the biological pathways involved in treatment response.

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See how nutrients can support mood.

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Building on the foundation of DEPLIN®

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What is DEPLIN®?

DEPLIN® is a medical food that provides targeted nutrition to support the brain pathways involved in mood regulation. Some people living with depression have unique nutritional needs that changes in diet alone cannot meet.¹


DEPLIN® helps nourish the biological foundation involved in the brain’s response to treatment. It is sold by prescription for people 12 years and older, to be used under medical supervision, and comes in two formulations.

How Nutrition Impacts Mood

Nutrition affects the pathways the brain uses to regulate mood. People with depression may need higher levels of certain nutrients, and for many, changes in diet alone isn’t enough to meet those needs.


When these needs aren’t met, the neurotransmitter systems involved in mood regulation may not function effectively — and this can affect how the brain responds to antidepressants, including a higher likelihood of side effects. Providing nutritional support helps reinforce these underlying biological processes.2

Is DeplinPRO Mood Health™ Right For You?

What It Is

DeplinPRO Mood Health™ builds on the science of DEPLIN® with a multi-ingredient formula that targets brain systems linked to mood regulation.

How It Works

Acts across multiple neurological pathways to help restore balance in brain chemistry and support effective treatment response.

Talk To Your Provider

Ask your healthcare provider whether DeplinPRO Mood Health™ is right for your depression care needs.

The ingredients in DeplinPRO Mood Health™ work to support:

Emotional Balance1,3-5

Brain Cell Wellness1,5-9

Mental Resilience8,10,11

Stress Management4,6,10

Cognitive Function5,6,10,12

DEPLIN® & Depression Resources

Patient Resources

Download a discussion guide to start the conversation with your provider, and find other resources on DEPLIN® and depression.
See Patient Resources

Request a Prescription

If you’re using an antidepressant but still not feeling your best, connect with a provider via telehealth to see if DEPLIN® can help you.
Request a Prescription

What people are saying§

"I love the product! It works so well for me...It made such a difference!"
"You guys should hire me to promote Deplin. It changed my life!" "I've been taking it for about 10 years...I have nothing but great things to say about Deplin. It seriously saved my life[.]"
"It's working! I'm happy to be taking it and happy with the results!"
"I've been on [Deplin] for almost three years and it has been an absolute godsend."
"You all are changing lives...After a DNA test, I found out, my body cant metabolize folate and when I started taking this, it changed everything."
"It’s a great product. I've used it for a while and it's helped me so much." "[Deplin] has really helped me...great product and very effective."
"Great [product]. It's made such a difference in my life."
"I started taking this when I was in a very dark place. I am so grateful[.]"
Get a Prescription

Deplin FC™ is a medical food specially formulated to meet the distinctive nutritional requirements for neurotransmitter imbalances in the clinical dietary management of depression & schizophrenia. Use under medical supervision.

DeplinPRO Mood Health™ is a medical food specially formulated to meet the distinctive nutritional requirements for neurotransmitter imbalances in the clinical dietary management of mood disorders. Use under medical supervision.

†Deplin FC™ (FC for “free & clear”) and DeplinPRO Mood Health™are free from major allergens: milk, eggs, fish or shellfish, sesame, tree nuts, peanuts, wheat, and soy.

*Based on US dollar sales through IQVIA NSP reporting channels from January 2023 – December 2024 of Deplin® branded medical foods compared to other branded medical foods indicated for depression.

§Real testimonials. Pictures and names are for illustrative purposes only.

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