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Deplin® helps your brain and antidepressant work better together

Targeted nutrition for people with depression

What is Deplin®?

Deplin® is targeted nutrition that provides an essential nutrient your body can’t get through diet alone to help restore brain chemistry balance. This allows your brain and antidepressant to work better together for more effective symptom relief.1 Deplin® is prescribed for use under medical supervision.

How Nutrition Impacts Mood

Proper nutrition plays a key role in mood and brain function. Nutrient deficiencies can interfere with cognitive performance and emotional well-being. Without the right nutrients, antidepressants may not work optimally, and side effects may increase. Addressing these deficiencies helps restore brain chemistry balance and supports recovery.2

Is Deplin® Right For You?

Deplin® is the #1 prescribed medical food brand for depression*. Ask your healthcare provider if Deplin® should be added to your current depression care.

Free & Clear

Deplin® offers Deplin FC™, a free and clear formula that provides 15mg of L-methylfolate to help your brain and antidepressant work better together.1,4

84% Symptom Reduction

In a clinical study, adding Deplin FC™ reduced depressive symptoms by up to 84% vs antidepressant alone. 3

No Added Side Effects

Safety profile is similar to placebo and not associated with weight gain or sexual dysfunction. 13

Deplin® & Depression Resources

Patient Resources

Download a discussion guide to start the conversation with your provider, and find other resources on Deplin® and depression.

Request a Prescription

If you’re using an antidepressant but still not feeling your best, connect with a provider via telehealth to see if Deplin® can help you.